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phagosome SUBST

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phagosome BIOL

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During normal phagocytosis, bacteria are enclosed by the phagosome, which fuses with the lysosome to become a phagolysosome. en.wikipedia.org

Within the phagosome the fungus has an absolute requirement for thiamine. en.wikipedia.org

Upon release from the phagosome, the toxin has reduced activity in the more basic cytosol. en.wikipedia.org

Once inside this phagocyte, the bacterium is trapped in a compartment called a phagosome. en.wikipedia.org

These liposomes may be digested while in the macrophage's phagosome, thus releasing its drug. en.wikipedia.org

The phagosome then combines with a lysosome to create a phagolysosome. en.wikipedia.org

They survive inside the phagosome. en.wikipedia.org

They grow and multiply inside the phagosome. en.wikipedia.org

When granules fuse with a phagosome, myeloperoxidase is released into the phagolysosome, and this enzyme uses hydrogen peroxide and chlorine to create hypochlorite, a substance used in domestic bleach. en.wikipedia.org

This enables the bacterium to escape the phagosome into the cytoplasm, where it can complete its lifecycle and multiply. phys.org

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