plasmin no Oxford-Paravia Italian Dictionary

Traduções para plasmin no dicionário inglês»italiano

plasmin [Brit ˈplazmɪn, americ ˈplæzmən] SUBST

plasmin

plasmina f

Traduções para plasmin no dicionário italiano»inglês

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plasmina

plasmin

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Plasmin, like trypsin, belongs to the family of serine proteases.

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It inhibits proteases like chymotrypsin, kallikrein, plasmin, thrombin, and trypsin.

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Activated plasminogen, plasmin, is a fundamental component of the fibrinolytic system and is the main enzyme involved in the lysis of blood clots and clearance of extravasated fibrin.

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Moreover, plasmin which is formed in excess in hyperfibrinolysis can proteolytically activate or inactivate many plasmatic or cellular proteins involved in hemostasis.

en.wikipedia.org

This drug is made by transgenic bacteria and it converts plasminogen into the clot-dissolving enzyme plasmin.

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The primary physiological substrate is plasminogen, which is an inactive form (zymogen) of the serine protease plasmin.

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These drugs block the binding sites of the enzymes or plasminogen respectively and thus stop plasmin formation.

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The protease plasmin still retains its enzymatic properties.

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As an enzyme, it catalyzes the conversion of plasminogen to plasmin, the major enzyme responsible for clot breakdown.

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At very low pressures this streaming inside the brain will cause a mild "stirring" action in which additional fibrin binding sites are exposed to plasmin.

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