Ungefähr gleichzeitig gewann die Anwendung kleiner RNAs für das gezielte Ausschalten von Genen in höheren Organismen ( RNA Interferenz ) an Fahrt.
Waren bis dahin im Modellbakterium Escherichia coli nur zehn kleine nichtkodierende RNAs (sRNAs) bekannt gewesen, stieg deren Zahl binnen kürzester Zeit auf nun über 60.
Weitere hunderte sRNAs sind bisher vorausgesagt, müssen allerdings noch verifiziert werden.
www.mpiib-berlin.mpg.deIn contrast, the regulatory potential of RNA appeared to be mainly confined to small antisense RNAs that control biological functions in bacterial plasmids, phages and transposons.
Small, noncoding RNAs (sRNAs) in the size range from 20 to 500 nucleotides were long regarded as a minor addition to the bulk of the known classes of cellular RNAs.
However, systematic searches keep discovering ever greater numbers of these molecules both in prokaryotes and in eukaryotes.
www.mpiib-berlin.mpg.deDeseja acrescentar uma palavra, uma frase ou uma tradução?
Envie-nos uma nova entrada.